Ever since I took ownership of the car I have had a vibrating noise coming form the rear trim panel in which the Bose Nd Woofer is installed. I've already had it back in the shop to have it repaired, but the problem is back again. Also, the overall quality of the Bose premium sound system is less than the factory installed system I had in my 1993 Camry. I have a six CD changer, but I can't cycle all six CD's in random order. My wife's 2001 Sienna allows her to do that.
Regarding your "vibration in the rear trim panel", check all knobs on your luggage rack and make sure they're tight.
Is there anything else besides the radio option. How's the reliability of the MDX?
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