My alternator went out at 170,000 miles.
My water pump went out at 190,000 miles.
My thermostat went out at 210,000 miles.
My S-10 Blazer has reached 220,000 miles and hasn't given me any serious trouble.
With the exception of routine maintenance (tires, oil, spark plugs, etc.) I have spent under $300 on repairs (doing all the work myself).
If you know anything about cars and how to take care of them, this is as tough a vehicle as you will find. My blazer has been through a lot and still runs smoother than my friends 2002 F-150 with 15,000mi.
I would drive it anywhere without thinking twice.
The last 50,000 miles have been pushing over-sized all-terrain tires. Still no problems, no lack of ability.
Can I have your truck!
Having troubles with mine... Will not idle. If I take my foot of the gas pedal it dies. Other than that I am out 4whelling and hunting all the time. Very dependable vehicle.