Nothing.
Very smooth driving, and comfortable seating. Very good view, controls well placed. Does shift a bit jerky at times, but no big deal. Running pretty much at 24 mpg most of time, varied driving. Towed my boat quite well, 1850 pounds, plus 450 for motor and? for heavy trailer. Does not have a lot of oomph at very low rpm when towing, Does real well once rpm hits 2k, not at all uncommon on V6 engines.
I use father's Blazer with a 4.3L and I find the similarities quite close in performance, but it only gets 21mpg in exact situation. Sure isn't near as comfortable as the sante, by a long shot. Father was quite impressed as well.
I have had some minor noise when I moved the roof rails into certain positions, easily cured that.
Now have 45K on the Sante. Only issue so far was the Bridgestone tires, which hydroplaned horribly. Replaced with Michelins and am very pleased with them. Still getting 24 MPG. Replaced the spark plugs which was a bit of work to move the engine forward to access them. Found very good directions on that process on the Sante Fe bulleting board.