Brake pads have had to be replaced twice.
Door locks don't work that well. Oftentimes the sliding door locks while you're trying to open it, then refuses to lock when you press the remote.
I've been very pleased with the reliability of this car. Overall, we've just had to do routine maintenance stuff. I've been told by the dealership that some of their Mercury Villagers, which are used as courtesy vehicles, are running up to 200K miles.
I just bought a 96' Villager. It runs superb, and it has 210,000 miles, still runs smooth as if it only had 50K. With some good keep-up of this vehicle, I plan on having it around for an addition 50+k miles.