First off, please don't comment about "no brakes" and all that jazz. The media can handle that for all of us.
I researched the Honda Insight, Ford Fusion Hybrid, and the Toyota Prius before I made my purchase. All of them are great cars. The deciding factors came down to cost, MPG, and overall design.
I chose the Prius because it has the highest MPG rating, and it's a hatch/wagon. I NEED a hatch/wagon for hauling all kinds of things. My '08 Civic was driving me nuts not being a wagon, but other than that I LOVED that car as well. If the Ford Fusion came as a wagon, it would have been a much more difficult decision.
On to the car! The Prius is great. It does everything I want it to do. I am averaging 52.5 MPG over the 6000 miles I have driven it since purchase. I commute about 1000 miles a week, and the savings are already adding up.
Comfort. I must admit the front seat on the base model is not very comfortable to me. I liked my Civic's seats much better, but the upgraded models with lumbar support might help that out. All controls for the car are easy to access and use. The stock base model radio is more than sufficient. I couldn't tell enough of a difference in the JBJ to upgrade to a Prius III, and I would never use the bluetooth function.
Performance. The car rides smoothly. Accelerates onto the highway with no issues at all. I live in Southern California where freeway speeds are often 80mph+ and I have never felt like I couldn't get up to speed to safely enter the highway. There is very little if any transition or "neck jerking" as I read in a comment when the ICE (internal combustion engine) comes on. It is smooth and under light acceleration often isn't noticed.
MPG. The car does as performed. Sort of. If you have a very short commute, say less than 10 miles, you will not see the true benefits of the hybrid. When you start the car the ICE comes on to warm up, and on a short trip may not spend much time off. On a week of vacation, all I was doing was running around town on less than 10 minute trips and I was averaging only 42mpg. A highway trip at the end brought my overall average up on the tank. I personally see better MPG on the highway.
Best - 55.7mpg, Worst - 49.9mpg, AVG - 52.5.
There are many capable hybrids and non-hybrid cars out there that can achieve excellent MPG. I hope this review helped out with your research.