The ball joints needed replacing.
The tie rods needed replacing.
In the four years we had the van the muffler rusted out three times.
The tires were going bald. Most likely from the worn out ball joints and tie rods.
The transmission would shudder on the 1-2 shift. Easing off the pedal would allow it to shift normally. That problem never got better, even after a transmission flush.
The gas mileage was very poor (10 mpg) when we got the van. After a computer diagnosis it was determined the Oxygen sensor sensor was faulty. Replacing it immediately doubled the mileage.
The air conditioning stopped working.
The thermostat stuck open in the middle of winter. This made for very cold drives to work until it was replaced.
The alternator failed once.
One day we went to put the transmission in reverse and the van would not reverse. From that point on we had park only in spaces we could drive out of. Very frustrating!