120,000 miles. Timing chain broke. Got lucky because the cylinder head is non-interference, which meant no broken valves.
150,000 miles. Clutch went out.
Between 150,000 miles and 200,000 miles, had starter go out, also water pump, heater switch broke, and blew out a head gasket. After replacing head gasket, it blew out again after 20,000 miles. I almost hauled the truck out to the gun range and used it for target practice at this point, but I'm glad I didn't. I had the cylinder head rebuilt and resurfaced, and used a copper spray adhesive on the head gasket prior to installation. I also torqued the head bolts down to 75 ft.lbs., versus the manufacturers recommendation of 58 ft. lbs. No more problems with the head gasket.
Another clutch at 200,000.
Another starter at 200,000.
Radiator had to be replaced at 225,000.
Chewed up my differential gears at 300,000. This was my fault, because I got stuck in the snow and had one tire spinning at 95 m.p.h. trying to get out. Never do this, unless you want to replace the rear end.
Finally at 350,000 miles, this truck is starting to fall apart. The speedometer cable howls like a banshee when the weather gets cold, and there are rattles and clunking sounds to numerous to mention. The engine makes a loud "thak thak thak" noise at idle. Probably the camshaft.
Other than the noise, the engine runs great, still gets 25 m.p.g. and still passes emissions.
Truly, the best, and most reliable vehicle I've ever owned.
I have no doubt the engine will make it to 400,000 miles, and at that point, I'll have to decide if I still want to keep it or not.